# SPIDER

**Repository Path**: itking666/SPIDER

## Basic Information

- **Project Name**: SPIDER
- **Description**: SPIDER  (System for Processing Image Data from Electron microscopy and Related fields) is an image processing system for electron microscopy, especially usefull for single-particle reconstruction.
- **Primary Language**: Unknown
- **License**: Not specified
- **Default Branch**: master
- **Homepage**: None
- **GVP Project**: No

## Statistics

- **Stars**: 0
- **Forks**: 1
- **Created**: 2020-03-07
- **Last Updated**: 2021-05-03

## Categories & Tags

**Categories**: Uncategorized

**Tags**: None

## README


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**SPIDER**  (**S**ystem for **P**rocessing **I**mage **D**ata from **E**lectron microscopy and **R**elated fields) 
is an image processing system for electron microscopy, especially usefull for single-particle reconstruction. 
[*SPIDER*](http://spider.wadsworth.org/spider_doc/spider/docs/spider.html) has been in use since 1978 and contains 
over 210,000 lines of Fortran code and 7400 files. 
The complete distribution can easily be downloaded from the 
[Wadsworth Center](http://spider.wadsworth.org/spider_doc/spider/docs/spi-register.html). 

The latest release contains support for reading/writing MRC files.

* Uses:
               
   1.  [Averaging of single particle objects](http://spider.wadsworth.org/spider_doc/spider/docs/philosophy.html) 
  
   2.  [Multivariate statistical analysis](http://spider.wadsworth.org/spider_doc/spider/docs/techs/MSA/index.html)
  
   3.  [3D reconstruction](http://spider.wadsworth.org/spider_doc/spider/docs/strategies.html)

   4.  [Electron tomography](http://spider.wadsworth.org/spider_doc/spider/docs/techs/lgstr/tomo/tomo.html)
                     
   5.  [Object segmentation from volumes](http://spider.wadsworth.org/spider_doc/spider/docs/techs/segment/segment.html)

        
* Features:
               
   1.   Interactive [command line interface](http://spider.wadsworth.org/spider_doc/spider/docs/user_doc.html).  

   2.   Hierarchical modular design for scripting.  

   3.   Graphical user interface, [*Web*](http://spider.wadsworth.org/spider_doc/web/docs/web.html), for 
        visualizing and interacting with images.  

   4.   Uses a [File format](http://spider.wadsworth.org/spider_doc/spider_doc/spider/docs/image_doc.html) 
        interchangeable with other electron microscopy imaging systems.  

   5.   Extensive [documentation](http://spider.wadsworth.org/spider_doc/spider/docs/documents.html) of 
                     [operations](http://spider.wadsworth.org/spider_doc/spider/docs/operations_doc.html) and
                     [techniques](http://spider.wadsworth.org/spider_doc/spider/docs/techniques.html).  
                  
   6.   Includes [source code](http://spider.wadsworth.org/spider_doc/spider/src) and executables for use on Linux. 
 
* History:

   1.   Originated in [1978](http://spider.wadsworth.org/spider_doc/spider/docs/spider78.html) by 
           [Joachim Frank](http://franklab.cpmc.columbia.edu/franklab) who
           shared the 2017 Nobel Prize in Chemistry for his pioneering cryo-em research done at the 
           [Wadsworth Center](http://www.wadsworth.org) in Albany, NY.
       
   2.  Contributors (in chronological order): 
          J. Frank,    B. Shimkin,   H. Dowse,       L. Miranda,  C. Mannella,   J. P. Bretaudiere, 
          M. V. Heel,  A. Verschoor, M. Radermacher, A. Leith,     J. M. Carazo, P. Penczek,    S. Sibal, 
          L. Odesanya, Y. H. Li,     M. Ladjadj,     Y. Chen,      K. R. Lata,   J. Zhu,        W. P. Liu,   B. Rath, 
          C. Yang,     B. Baxter,    R. Hegerl,      A. Frangakis, L. Joyeux,    Z. Huang,      R. J. Renka, 
          T. Shaikh,   J. Sengupta,  J. LeBarron,    N. Boisset,   H. Gao,       G. Kishchenko, J. M. Kennedy.
                
          In addition SPIDER is dependent on the Fourier package [FFTW](http://www.fftw.org) by M. Frigo and SG Johnson.  
               
   3.   Maintained since 2007 by: ArDean Leith & Tanvir Shaikh. During these 12 years they added numerous 
        operations, procedures, parallelizations, and over 500 pages of documentation.  There have been no 
        significant contributors other than Leith, Shaikh, Kischenko, and Kennedy since 2007.

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[Copyright under GPL](http://spider.wadsworth.org/spider_doc/spider/docs/copyright.html).